10% of immunized volunteers reported the side effect after the first dose (compared to 5% on placebo), and 14% noted it after the second booster shot (compared to 4% of the placebo group). There were no vaccine-related adverse effects on female fertility, pregnancy, embryo foetal or offspring development or postnatal development. Those arm-specific side effects were most commonly pain and swelling of the armpit's lymph nodes.Ĭhanges in the size and consistency of lymph nodes in the armpit was a common side effect that typically lasted one or two days. While the vast majority of reactions lasted two or three days, some participants had side effects that lasted longer than a week.12% of participants had typical body-wide side effects, such as fatigue or headache, that lasted longer than seven days, compared to 10% of the placebo group.Ībout 4% had reactions related to the injected arm that lasted more than a week after an injection compared to 1% of the placebo group. These were still expected, and the reactions to the shots were typically fleeting. For these people, the reactions were strong enough to hinder daily living activities. The Pfizer and Moderna vaccines are both mRNA vaccines, the Novavax vaccine is a protein subunit. Therefore, we aimed to systematically review the adverse events related to the mRNA vaccines reported in the literature. These consisted of either reactions at the injection site, like pain or swelling, or systemic reactions to the vaccine, like fever, headache, fatigue, nausea, and vomiting. Adverse reactions or side effects after receiving COVID-19 vaccine High-grade fever Heart palpitation defined as a fast-beating, fluttering or pounding heart. Introduction: Knowledge of vaccine-related adverse events is crucial as they are among the most important factors that cause hesitation in receiving vaccines. It often indicates a user profile.ġ6.5% of those who got Moderna's vaccine reported severe side effects compared to 3.7% on placebo.
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